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Rat Trip4 cDNA Clone(NM_001134981.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010077

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Gene Information

Cat. No. CDFR010077
Description NativeORF clone of Rattus norvegicus thyroid hormone receptor interactor 4 (Trip4) as transfection-ready DNA NM_001134981.1
Product Type cDAN Clone
Gene Abbr Trip4
Species Rat
Vector pCMV6Entry
Target Gene TRIP4
Background This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1). [provided by RefSeq, Apr 2016]
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