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Rat Trim5 cDNA Clone(NM_001014023.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003159

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Gene Information

Cat. No. CDFR003159
Description NativeORF clone of Rattus norvegicus similar to 9230105E10Rik protein (RGD1304579) as transfection-ready DNA NM_001014023.1
Product Type cDAN Clone
Gene Abbr Trim5
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TRIM5
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]
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