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Rat Trim2 cDNA Clone(NM_001108552.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008161

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Gene Information

Cat. No. CDFR008161
Description NativeORF clone of Rattus norvegicus tripartite motif protein 2 (Trim2) as transfection-ready DNA NM_001108552.1
Product Type cDAN Clone
Gene Abbr Trim2
Species Rat
Vector pCMV6Entry
Target Gene TRIM2
Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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