Rat Tpt1 cDNA Clone(NM_053867.1)

Name: Rat Tpt1 cDNA Clone(NM_053867.1)
SKU: CDFR013597
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013597

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Product Information

Gene Information

Cat. No.	CDFR013597
Description	NativeORF clone of Rattus norvegicus tumor protein, translationally-controlled 1 (Tpt1) as transfection-ready DNA NM_053867.1
Product Type	cDAN Clone
Gene Abbr	Tpt1
Species	Rat
Vector	pCMV6Entry

Target Gene

TPT1

Background

This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

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