Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR379695
| Cat. No. | CDCR379695 |
| Product Type | ORF Clone |
| Gene Abbr | Tpp1 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 1692 bp |
| Vector | pCMV6-Entry |
| Target Gene | TPP1 |
| Background | This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008] |
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