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Rat Tmem107 cDNA Clone(NM_001109648.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009177

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Gene Information

Cat. No. CDFR009177
Description NativeORF clone of Rattus norvegicus hypothetical protein LOC691750 (LOC691750) as transfection-ready DNA NM_001109648.1
Product Type cDAN Clone
Gene Abbr Tmem107
Species Rat
Vector pCMV6Entry
Target Gene TMEM107
Background This gene encodes a transmembrane protein and component of the primary cilia transition zone. The encoded protein regulates ciliogenesis and ciliary protein composition. Human fibroblasts expressing a mutant allele of this gene exhibit reduced numbers of cilia, altered cilia length, and impaired sonic hedgehog signaling. In human patients, different mutations in this gene cause different ciliopathies, including Meckel-Gruber syndrome and orofaciodigital syndrome. [provided by RefSeq, May 2017]
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