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Rat Tmed10 ORF Clone(NM_053467.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR380286

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Product Information

Gene Information

Cat. No. CDCR380286
Product Type ORF Clone
Gene Abbr Tmed10
Species Rat
Tag C-terminal Myc-DDK
ORF Size 660 bp
Vector pCMV6-Entry
Target Gene TMED10
Background This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
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