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Rat Tln1 cDNA Clone(NM_001039025.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003924

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Gene Information

Cat. No. CDFR003924
Description NativeORF clone of Rattus norvegicus talin 1 (Tln1) as transfection-ready DNA NM_001039025.2
Product Type cDAN Clone
Gene Abbr Tln1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TLN1
Background This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009]
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