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Rat Timeless cDNA Clone(NM_031340.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012645

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Gene Information

Cat. No. CDFR012645
Description NativeORF clone of Rattus norvegicus timeless homolog (Drosophila) (Timeless) as transfection-ready DNA NM_031340.1
Product Type cDAN Clone
Gene Abbr Timeless
Species Rat
Vector pCMV6Entry
Target Gene TIMELESS
Background The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. [provided by RefSeq, Feb 2014]
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