Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR003180
| Cat. No. | CDFR003180 |
| Description | NativeORF clone of Rattus norvegicus TRAF-interacting protein with forkhead-associated domain (Tifa) as transfection-ready DNA NM_001014044.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Tifa |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | TIFA |
| Background | This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018] |
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