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Rat Tia1 cDNA Clone(NM_001012096.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002524

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Gene Information

Cat. No. CDFR002524
Description NativeORF clone of Rattus norvegicus TIA1 cytotoxic granule-associated RNA binding protein (Tia1) as transfection-ready DNA NM_001012096.1
Product Type cDAN Clone
Gene Abbr Tia1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TIA1
Background The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms has been found for this gene. [provided by RefSeq, May 2017]
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