Rat Tgfb3 cDNA Clone(NM_013174.2)

Name: Rat Tgfb3 cDNA Clone(NM_013174.2)
SKU: CDFR011014
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR011014

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Product Information

Gene Information

Cat. No.	CDFR011014
Description	NativeORF clone of Rattus norvegicus transforming growth factor, beta 3 (Tgfb3) as transfection-ready DNA NM_013174.2
Product Type	cDAN Clone
Gene Abbr	Tgfb3
Species	Rat
Vector	pCMV6Entry

Target Gene

TGFB3

Background

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]

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