Rat Tgds cDNA Clone(NM_001107286.1)

Name: Rat Tgds cDNA Clone(NM_001107286.1)
SKU: CDFR007005
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007005

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Product Information

Gene Information

Cat. No.	CDFR007005
Description	NativeORF clone of Rattus norvegicus TDP-glucose 4,6-dehydratase (Tgds) as transfection-ready DNA NM_001107286.1
Product Type	cDAN Clone
Gene Abbr	Tgds
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

TGDS

Background

The protein encoded by this gene is a member of the short-chain dehydrogenases/reductases (SDR) superfamily, and is thought to contain a nicotinamide adenine dinucleotide (NAD) binding domain. This large SDR family of enzymes is involved in the metabolism of a variety of compounds, including prostaglandins, retinoids, lipids, steroid hormones, and xenobiotics. Mutations in this gene have been associated with Catel-Manzke syndrome, which is characterized by Pierre Robin sequence, and radial deviation of the index finger due to the presence of an accessory bone between the index finger and its proximal phalanx. Pierre Robin sequence is defined by an undersized jaw, backwards displacement of the tongue base that causes an obstruction of the airways, and can also be associated with a cleft palate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

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