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Rat Tcof1 cDNA Clone(NM_001106143.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005904

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Gene Information

Cat. No. CDFR005904
Description NativeORF clone of Rattus norvegicus Treacher Collins Franceschetti syndrome 1, homolog (Tcof1) as transfection-ready DNA NM_001106143.1
Product Type cDAN Clone
Gene Abbr Tcof1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TCOF1
Background This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
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