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Rat Tbx21 cDNA Clone(NM_001107043.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006751

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Gene Information

Cat. No. CDFR006751
Description NativeORF clone of Rattus norvegicus T-box 21 (Tbx21) as transfection-ready DNA NM_001107043.1
Product Type cDAN Clone
Gene Abbr Tbx21
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TBX21
Background This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx21/Tbet gene. Studies in mouse show that Tbx21 protein is a Th1 cell-specific transcription factor that controls the expression of the hallmark Th1 cytokine, interferon-gamma (IFNG). Expression of the human ortholog also correlates with IFNG expression in Th1 and natural killer cells, suggesting a role for this gene in initiating Th1 lineage development from naive Th precursor cells. [provided by RefSeq, Jul 2008]
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