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Rat Taf6l cDNA Clone(NM_001107575.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006885

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Gene Information

Cat. No. CDFR006885
Description NativeORF clone of Rattus norvegicus TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor (Taf6l) as transfection-ready DNA NM_001107575.1
Product Type cDAN Clone
Gene Abbr Taf6l
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene TAF6L
Background Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation. [provided by RefSeq, Jul 2008]
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