Rat Taf12 ORF Clone(NM_001115036.1)

Name: Rat Taf12 ORF Clone(NM_001115036.1)
SKU: CDCR376419
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR376419

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Product Information

Gene Information

Cat. No.	CDCR376419
Product Type	ORF Clone
Gene Abbr	Taf12
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	486 bp
Vector	pCMV6-Entry

Target Gene

TAF12

Background

Control of transcription by RNA polymerase II involves the basal transcription machinery which is a collection of proteins. These proteins with RNA polymerase II, assemble into complexes which are modulated by transactivator proteins that bind to cis-regulatory elements located adjacent to the transcription start site. Some modulators interact directly with the basal complex, whereas others may act as bridging proteins linking transactivators to the basal transcription factors. Some of these associated factors are weakly attached while others are tightly associated with TBP in the TFIID complex. Among the latter are the TAF proteins. Different TAFs are predicted to mediate the function of distinct transcriptional activators for a variety of gene promoters and RNA polymerases. TAF12 interacts directly with TBP as well as with TAF2I. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2008]

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