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Rat TGFBI ORF clone(NM_053802.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCG000269

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Product Information

Gene Information

Cat. No. CDCG000269
Product Type ORF clone
Gene Abbr TGFBI
Species Rat
Host Cell Bacterial
Source Bacteria
ORF Size 2696bp
Size 1ug
Format Clear Liquid
Vector pORF
Buffer 10mM Tris-HCI, 1mM EDTA, pH8.0
Warning pORF-rTgfbi ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage 1 year when stored at -20°C or lower in a non-frost free freezer.
Target Gene TGFBI
Background This gene encodes an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. This protein plays a role in cell-collagen interactions and may be involved in endochondrial bone formation in cartilage. The protein is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in this gene are associated with multiple types of corneal dystrophy. [provided by RefSeq, Jul 2008]
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