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Rat Sulf2 ORF Clone(NM_001034927.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371442

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Gene Information

Cat. No. CDCR371442
Product Type ORF Clone
Gene Abbr Sulf2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 2628 bp
Vector pCMV6-Entry
Target Gene SULF2
Background Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]
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