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Rat Stc1 ORF Clone(NM_031123.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379496

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Gene Information

Cat. No. CDCR379496
Product Type ORF Clone
Gene Abbr Stc1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 744 bp
Vector pCMV6-Entry
Target Gene STC1
Background This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq, Jul 2008]
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