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Rat Srd5a3 cDNA Clone(NM_001013990.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003066

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Gene Information

Cat. No. CDFR003066
Description NativeORF clone of Rattus norvegicus steroid 5 alpha-reductase 3 (Srd5a3) as transfection-ready DNA NM_001013990.1
Product Type cDAN Clone
Gene Abbr Srd5a3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SRD5A3
Background The protein encoded by this gene belongs to the steroid 5-alpha reductase family, and polyprenol reductase subfamily. It is involved in the production of androgen 5-alpha-dihydrotestosterone (DHT) from testosterone, and maintenance of the androgen-androgen receptor activation pathway. This protein is also necessary for the conversion of polyprenol into dolichol, which is required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-linked glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type Iq. [provided by RefSeq, Mar 2011]
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