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Rat Sptan1 cDNA Clone(NM_171983.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR014683

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Gene Information

Cat. No. CDFR014683
Description NativeORF clone of Rattus norvegicus alpha-spectrin 2 (Spna2) as transfection-ready DNA NM_171983.2
Product Type cDAN Clone
Gene Abbr Sptan1
Species Rat
Vector pCMV6Entry
Target Gene SPTAN1
Background Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles. Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement. This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells. The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation. Mutations in this gene are the cause of early infantile epileptic encephalopathy-5. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
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