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Rat Spta1 cDNA Clone(NM_001011908.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002338

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Gene Information

Cat. No. CDFR002338
Description NativeORF clone of Rattus norvegicus spectrin, alpha, erythrocytic 1 (elliptocytosis 2) (Spta1) as transfection-ready DNA NM_001011908.3
Product Type cDAN Clone
Gene Abbr Spta1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SPTA1
Background This gene encodes a member of a family of molecular scaffold proteins that link the plasma membrane to the actin cytoskeleton and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms a component of the erythrocyte plasma membrane. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis-2, pyropoikilocytosis, and spherocytosis, type 3. [provided by RefSeq, Aug 2017]
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