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Rat Sphk2 cDNA Clone(NM_001012066.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002493

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Gene Information

Cat. No. CDFR002493
Description NativeORF clone of Rattus norvegicus sphingosine kinase 2 (Sphk2) as transfection-ready DNA NM_001012066.1
Product Type cDAN Clone
Gene Abbr Sphk2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SPHK2
Background This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
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