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Rat Spa17 cDNA Clone(NM_053482.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013212

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Gene Information

Cat. No. CDFR013212
Description NativeORF clone of Rattus norvegicus sperm autoantigenic protein 17 (Spa17) as transfection-ready DNA NM_053482.1
Product Type cDAN Clone
Gene Abbr Spa17
Species Rat
Vector pCMV6Entry
Target Gene SPA17
Background This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.[provided by RefSeq, Jan 2009]
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