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Rat Sox2 ORF Clone(NM_001109181.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR375812

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Product Information

Gene Information

Cat. No. CDCR375812
Product Type ORF Clone
Gene Abbr Sox2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 960 bp
Vector pCMV6-Entry
Target Gene SOX2
Background This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT). [provided by RefSeq, Jul 2008]
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