Rat Sorbs2 cDNA Clone(NM_053770.1)

Name: Rat Sorbs2 cDNA Clone(NM_053770.1)
SKU: CDFR013518
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR013518

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Product Information

Gene Information

Cat. No.	CDFR013518
Description	NativeORF clone of Rattus norvegicus Arg/Abl-interacting protein ArgBP2 (Argbp2) as transfection-ready DNA NM_053770.1
Product Type	cDAN Clone
Gene Abbr	Sorbs2
Species	Rat
Vector	pCMV6Entry

Target Gene

SORBS2

Background

Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. This gene encodes the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

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