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Rat Socs3 cDNA Clone(NM_053565.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013288

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Gene Information

Cat. No. CDFR013288
Description NativeORF clone of Rattus norvegicus suppressor of cytokine signaling 3 (Socs3) as transfection-ready DNA NM_053565.1
Product Type cDAN Clone
Gene Abbr Socs3
Species Rat
Vector pCMV6Entry
Target Gene SOCS3
Background This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. [provided by RefSeq, Jul 2008]
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