Transfected Stable Cell Lines
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Cat. No. : CDFR006274
| Cat. No. | CDFR006274 |
| Description | NativeORF clone of Rattus norvegicus syntrophin, gamma 2 (Sntg2) as transfection-ready DNA NM_001106720.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Sntg2 |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | SNTG2 |
| Background | This gene encodes a protein belonging to the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that bind to components of mechanosenstive sodium channels and the extreme carboxy-terminal domain of dystrophin and dystrophin-related proteins. The PDZ domain of this protein product interacts with a protein component of a mechanosensitive sodium channel that affects channel gating. Absence or reduction of this protein product has been associated with Duchenne muscular dystrophy. There is evidence of alternative splicing yet the full-length nature of these variants has not been described. [provided by RefSeq, Jul 2008] |
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