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Rat Smarce1 cDNA Clone(NM_001024993.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR003773

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Gene Information

Cat. No. CDFR003773
Description NativeORF clone of Rattus norvegicus SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 (Smarce1) as transfection-ready DNA NM_001024993.1
Product Type cDAN Clone
Gene Abbr Smarce1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SMARCE1
Background The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq, Jul 2008]
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