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Rat Smarcal1 cDNA Clone(NM_001108222.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007863

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Gene Information

Cat. No. CDFR007863
Description NativeORF clone of Rattus norvegicus Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 (Smarcal1) as transfection-ready DNA NM_001108222.1
Product Type cDAN Clone
Gene Abbr Smarcal1
Species Rat
Vector pCMV6Entry
Target Gene SMARCAL1
Background The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency. [provided by RefSeq, Jul 2008]
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