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Rat Slc52a2 cDNA Clone(NM_001109670.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009192

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Gene Information

Cat. No. CDFR009192
Description NativeORF clone of Rattus norvegicus G protein-coupled receptor 172B (Gpr172b) as transfection-ready DNA NM_001109670.1
Product Type cDAN Clone
Gene Abbr Slc52a2
Species Rat
Vector pCMV6Entry
Target Gene SLC52A2
Background This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012]
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