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Rat Slc29a1 cDNA Clone(NM_031684.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012820

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Gene Information

Cat. No. CDFR012820
Description NativeORF clone of Rattus norvegicus solute carrier family 29 (nucleoside transporters), member 1 (Slc29a1), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_031684.2
Product Type cDAN Clone
Gene Abbr Slc29a1
Species Rat
Vector pCMV6Entry
Target Gene SLC29A1
Background This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
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