Rat Slc25a19 cDNA Clone(NM_001007674.1)

Name: Rat Slc25a19 cDNA Clone(NM_001007674.1)
SKU: CDFR001682
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001682

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Product Information

Gene Information

Cat. No.	CDFR001682
Description	NativeORF clone of Rattus norvegicus solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19 (Slc25a19), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001007674.1
Product Type	cDAN Clone
Gene Abbr	Slc25a19
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

SLC25A19

Background

This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

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