Rat Slc22a5 cDNA Clone(NM_019269.1)

Name: Rat Slc22a5 cDNA Clone(NM_019269.1)
SKU: CDFR011560
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR011560

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Product Information

Gene Information

Cat. No.	CDFR011560
Description	NativeORF clone of Rattus norvegicus solute carrier family 22 (organic cation/carnitine transporter), member 5 (Slc22a5) as transfection-ready DNA NM_019269.1
Product Type	cDAN Clone
Gene Abbr	Slc22a5
Species	Rat
Vector	pCMV6Entry

Target Gene

SLC22A5

Background

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2015]

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