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Rat Slc11a1 cDNA Clone(NM_001031658.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004193

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Gene Information

Cat. No. CDFR004193
Description NativeORF clone of Rattus norvegicus solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 (Slc11a1) as transfection-ready DNA NM_001031658.1
Product Type cDAN Clone
Gene Abbr Slc11a1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SLC11A1
Background This gene is a member of the solute carrier family 11 (proton-coupled divalent metal ion transporters) family and encodes a multi-pass membrane protein. The protein functions as a divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Mutations in this gene have been associated with susceptibility to infectious diseases such as tuberculosis and leprosy, and inflammatory diseases such as rheumatoid arthritis and Crohn disease. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined. [provided by RefSeq, Jul 2008]
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