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Rat Sirt6 cDNA Clone(NM_001031649.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004183

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Gene Information

Cat. No. CDFR004183
Description NativeORF clone of Rattus norvegicus sirtuin 6 (silent mating type information regulation 2, homolog) 6 (S. cerevisiae) (Sirt6) as transfection-ready DNA NM_001031649.1
Product Type cDAN Clone
Gene Abbr Sirt6
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SIRT6
Background This gene encodes a member of the sirtuin family of NAD-dependent enzymes that are implicated in cellular stress resistance, genomic stability, aging and energy homeostasis. The encoded protein is localized to the nucleus, exhibits ADP-ribosyl transferase and histone deacetylase activities, and plays a role in DNA repair, maintenance of telomeric chromatin, inflammation, lipid and glucose metabolism. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
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