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Rat Sirt2 cDNA Clone(NM_001008368.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001830

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Gene Information

Cat. No. CDFR001830
Description NativeORF clone of Rattus norvegicus sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) (Sirt2) as transfection-ready DNA NM_001008368.1
Product Type cDAN Clone
Gene Abbr Sirt2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SIRT2
Background This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
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