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Rat Sim2 ORF Clone(NM_001107108.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373837

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Product Information

Gene Information

Cat. No. CDCR373837
Gene Abbr Sim2
Species Rat
Tag C-terminal Myc-DDK
Vector pCMV6-Entry
Target Gene SIM2
Background This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
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