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Rat Shmt2 cDNA Clone(NM_001008322.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001784

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Gene Information

Cat. No. CDFR001784
Description NativeORF clone of Rattus norvegicus serine hydroxymethyltransferase 2 (mitochondrial) (Shmt2), nuclear gene encoding mitochondrial protein as transfection-ready DNA NM_001008322.1
Product Type cDAN Clone
Gene Abbr Shmt2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SHMT2
Background This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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