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Rat Sf3b2 cDNA Clone(NM_001106326.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006070

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Gene Information

Cat. No. CDFR006070
Description NativeORF clone of Rattus norvegicus splicing factor 3b, subunit 2 (Sf3b2) as transfection-ready DNA NM_001106326.1
Product Type cDAN Clone
Gene Abbr Sf3b2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SF3B2
Background This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
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