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Rat Set cDNA Clone(NM_001012504.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002745

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Gene Information

Cat. No. CDFR002745
Description NativeORF clone of Rattus norvegicus SET nuclear oncogene (Set) as transfection-ready DNA NM_001012504.1
Product Type cDAN Clone
Gene Abbr Set
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SET
Background The protein encoded by this gene inhibits acetylation of nucleosomes, especially histone H4, by histone acetylases (HAT). This inhibition is most likely accomplished by masking histone lysines from being acetylated, and the consequence is to silence HAT-dependent transcription. The encoded protein is part of a complex localized to the endoplasmic reticulum but is found in the nucleus and inhibits apoptosis following attack by cytotoxic T lymphocytes. This protein can also enhance DNA replication of the adenovirus genome. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
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