Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR013527
| Cat. No. | CDFR013527 |
| Description | NativeORF clone of Rattus norvegicus serine (or cysteine) peptidase inhibitor, clade I, member 1 (Serpini1) as transfection-ready DNA NM_053779.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Serpini1 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | SERPINI1 |
| Background | This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008] |
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