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Rat Serpine1 cDNA Clone(NM_012620.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010439

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Gene Information

Cat. No. CDFR010439
Description NativeORF clone of Rattus norvegicus serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) as transfection-ready DNA NM_012620.1
Product Type cDAN Clone
Gene Abbr Serpine1
Species Rat
Vector pCMV6Entry
Target Gene SERPINE1
Background This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. [provided by RefSeq, Aug 2020]
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