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Rat Sept7 cDNA Clone(NM_022616.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012048

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Gene Information

Cat. No. CDFR012048
Description NativeORF clone of Rattus norvegicus septin 7 (Sept7), transcript variant 1 as transfection-ready DNA NM_022616.2
Product Type cDAN Clone
Gene Abbr Sept7
Species Rat
Vector pCMV6Entry
Target Gene SEPT7
Background This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011]
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