Rat Sema6d cDNA Clone(NM_001107768.1)

Name: Rat Sema6d cDNA Clone(NM_001107768.1)
SKU: CDFR007300
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR007300

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Product Information

Gene Information

Cat. No.	CDFR007300
Description	NativeORF clone of Rattus norvegicus sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (Sema6d) as transfection-ready DNA NM_001107768.1
Product Type	cDAN Clone
Gene Abbr	Sema6d
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

SEMA6D

Background

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]

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