Rat Seli cDNA Clone(NM_001134754.1)

Name: Rat Seli cDNA Clone(NM_001134754.1)
SKU: CDFR009993
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR009993

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Product Information

Gene Information

Cat. No.	CDFR009993
Description	NativeORF clone of Rattus norvegicus selenoprotein I (Seli) as transfection-ready DNA NM_001134754.1
Product Type	cDAN Clone
Gene Abbr	Seli
Species	Rat
Vector	pCMV6Entry

Target Gene

SELI

Background

The multi-pass transmembrane protein encoded by this gene belongs to the CDP-alcohol phosphatidyltransferase class-I family. It catalyzes the transfer of phosphoethanolamine from CDP-ethanolamine to diacylglycerol to produce phosphatidylethanolamine, which is involved in the formation and maintenance of vesicular membranes, regulation of lipid metabolism, and protein folding. This protein is a selenoprotein, containing the rare selenocysteine (Sec) amino acid at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]

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