Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR012706
| Cat. No. | CDFR012706 |
| Description | NativeORF clone of Rattus norvegicus sodium channel, nonvoltage-gated, type I, alpha (Scnn1a) as transfection-ready DNA NM_031548.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Scnn1a |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | SCNN1A |
| Background | Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009] |
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