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Rat Scnn1a cDNA Clone(NM_031548.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012706

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Gene Information

Cat. No. CDFR012706
Description NativeORF clone of Rattus norvegicus sodium channel, nonvoltage-gated, type I, alpha (Scnn1a) as transfection-ready DNA NM_031548.2
Product Type cDAN Clone
Gene Abbr Scnn1a
Species Rat
Vector pCMV6Entry
Target Gene SCNN1A
Background Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2009]
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