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Rat Sap18 cDNA Clone(NM_001033685.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004244

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Gene Information

Cat. No. CDFR004244
Description NativeORF clone of Rattus norvegicus Sin3-associated polypeptide 18 (Sap18) as transfection-ready DNA NM_001033685.2
Product Type cDAN Clone
Gene Abbr Sap18
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene SAP18
Background Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2008]
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