Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR015112
| Cat. No. | CDFR015112 |
| Description | NativeORF clone of Rattus norvegicus rhotekin (Rtkn) as transfection-ready DNA NM_184046.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Rtkn |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | RTKN |
| Background | This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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